Nature Communications (Jun 2022)

Simple synthesis of massively parallel RNA microarrays via enzymatic conversion from DNA microarrays

  • Erika Schaudy,
  • Kathrin Hölz,
  • Jory Lietard,
  • Mark M. Somoza

DOI
https://doi.org/10.1038/s41467-022-31370-9
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 9

Abstract

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RNA microarrays have many potential applications, but are difficult to produce. Here, the AUs present a method for converting commercial, customizable DNA microarrays into RNA microarrays using an accessible three-step process involving primer photocrosslinking, extension, and template degradation.