Nature Communications (May 2020)

Characterization of the development of the mouse cochlear epithelium at the single cell level

  • Likhitha Kolla,
  • Michael C. Kelly,
  • Zoe F. Mann,
  • Alejandro Anaya-Rocha,
  • Kathryn Ellis,
  • Abigail Lemons,
  • Adam T. Palermo,
  • Kathy S. So,
  • Joseph C. Mays,
  • Joshua Orvis,
  • Joseph C. Burns,
  • Ronna Hertzano,
  • Elizabeth C. Driver,
  • Matthew W. Kelley

DOI
https://doi.org/10.1038/s41467-020-16113-y
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 16

Abstract

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How the development of the cochlear epithelium is regulated is unclear. Here, the authors use single cell RNAseq analysis to provide insight into the transcriptional changes arising during development of the murine cochlear inner and outer hair cells.