Terminalia chebula 10% Mouth Rinse, Topical Curcumin Oral Gel and Topical 0.1% Triamcinolone Acetonide Oromucosal Paste in the Management of Oral Aphthous Ulcers - An Interventional Study

Abstract

Background: Oral aphthous ulcers are the most common oral mucosal lesion without any definite remedy. Terminalia chebula is known as the “king of medicine” as it possesses extraordinary healing properties. To our knowledge, based on a literature search, there is no published study so far available using T. chebula mouth rinse alone in the treatment of recurrent aphthous ulcers (RAU). Hence, we aim to compare the effectiveness of triamcinolone acetonide oro-mucosal paste and curcumin oral gel, which are currently being used for the treatment of RAU, with that of T. chebula. Materials and Methods: This clinical interventional study involving 30 patients who were clinically diagnosed with minor aphthous ulcers were randomly divided into three groups: T. chebula 10% mouth rinse, topical application of curcumin oral gel, and 0.1% triamcinolone acetonide group with single blinding. The patients were reviewed for pain reduction, and the number and size of the ulcers were assessed. Results: Regarding the reduction in the size and number of the lesions, the T. chebula group produced superior results. Conclusion: T. chebula can be incorporated in the form of mouth rinse as an adjunct or alone effectively in the management of minor RAU, especially when other medications are contraindicated.

Keywords

• curcumin
• recurrent aphthous ulcers
• terminalia chebula
• triamcinolone acetonide