789 Immune checkpoint blockade augments cyclophosphamide induced anti-tumor immunity by expanding effector CD8+ T cell clones in a preclinical melanoma model

• Alan N Houghton,
• Jedd D Wolchok,
• Taha Merghoub,
• Daniel Hirschhorn,
• Linda Hamadene,
• Yacine Marouf,
• Allison B Warner,
• Mariam M George,
• Nicholas J Ceglia

Affiliations

Alan N Houghton

Aff4 grid.51462.340000000121719952Department of MedicineMemorial Sloan Kettering Cancer Center 10065 New York NY USA

Jedd D Wolchok

1Weill Cornell Medicine, New York, NY, USA

Taha Merghoub

1Weill Cornell Medicine, New York, NY, USA

Daniel Hirschhorn

1Weill Cornell Medicine, New York, NY, USA

Linda Hamadene

1Memorial Sloan-Kettering Cancer Center, New York, NY, USA

Yacine Marouf

1Weill Cornell Medicine, New York, NY, USA

Allison B Warner

4Memorial Sloan Kettering Cancer Center, New York, NY, USA

Mariam M George

1Weill Cornell Medicine, New York, NY, USA

Nicholas J Ceglia

2Memorial Sloan Kettering Cancer Center, New York, NY, USA