TiO<sub>2</sub>-MXene/PEDOT:PSS Composite as a Novel Electrochemical Sensing Platform for Sensitive Detection of Baicalein
Shuya Xue,
Min Shi,
Jinye Wang,
Jiapeng Li,
Guanwei Peng,
Jingkun Xu,
Yansha Gao,
Xuemin Duan,
Limin Lu
Affiliations
Shuya Xue
Flexible Electronics Innovation Institute (FEII), Jiangxi Science and Technology Normal University, Nanchang 330013, China
Min Shi
Flexible Electronics Innovation Institute (FEII), Jiangxi Science and Technology Normal University, Nanchang 330013, China
Jinye Wang
Shandong Liaocheng Ecological Environment Monitoring Center, Liaocheng 252000, China
Jiapeng Li
Flexible Electronics Innovation Institute (FEII), Jiangxi Science and Technology Normal University, Nanchang 330013, China
Guanwei Peng
Key Laboratory of Crop Physiology, Ecology and Genetic Breeding, Ministry of Education, Key Laboratory of Chemical Utilization of Plant Resources of Nanchang, College of Chemistry and Materials, Jiangxi Agricultural University, Nanchang 330045, China
Jingkun Xu
Flexible Electronics Innovation Institute (FEII), Jiangxi Science and Technology Normal University, Nanchang 330013, China
Yansha Gao
Key Laboratory of Crop Physiology, Ecology and Genetic Breeding, Ministry of Education, Key Laboratory of Chemical Utilization of Plant Resources of Nanchang, College of Chemistry and Materials, Jiangxi Agricultural University, Nanchang 330045, China
Xuemin Duan
Flexible Electronics Innovation Institute (FEII), Jiangxi Science and Technology Normal University, Nanchang 330013, China
Limin Lu
Key Laboratory of Crop Physiology, Ecology and Genetic Breeding, Ministry of Education, Key Laboratory of Chemical Utilization of Plant Resources of Nanchang, College of Chemistry and Materials, Jiangxi Agricultural University, Nanchang 330045, China
In this work, TiO2-MXene/poly (3,4-ethylenedioxythiophene): poly(styrenesulfonate) (PEDOT:PSS) composite was utilized as an electrode material for the sensitive electrochemical detection of baicalein. The in-situ growth of TiO2 nanoparticles on the surface of MXene nanosheets can effectively prevent their aggregation, thus presenting a significantly large specific surface area and abundant active sites. However, the partial oxidation of MXene after calcination could reduce its conductivity. To address this issue, herein, PEDOT:PSS films were introduced to disperse the TiO2-MXene materials. The uniform and dense films of PEDOT:PSS not only improved the conductivity and dispersion of TiO2-MXene but also enhanced its stability and electrocatalytic activity. With the advantages of a composite material, TiO2-MXene/PEDOT:PSS as an electrode material demonstrated excellent electrochemical sensing ability for baicalein determination, with a wide linear response ranging from 0.007 to 10.0 μM and a lower limit of detection of 2.33 nM. Furthermore, the prepared sensor displayed good repeatability, reproducibility, stability and selectivity, and presented satisfactory results for the determination of baicalein in human urine sample analysis.
