Frontiers in Medicine (Jun 2022)

Severe Thrombocytopenia Caused by Vancomycin in the Intensive Care Unit: A Case Report

  • Xiao-xiao Li,
  • Xiao-xiao Li,
  • Guan-ru Wang,
  • Guan-ru Wang,
  • Chao Li,
  • Na He,
  • Na He,
  • Peng Yao,
  • Yin-chu Cheng,
  • Chu-hui Wang,
  • Chu-hui Wang,
  • Qing-gang Ge,
  • Min Yi,
  • Zong-yu Wang,
  • Lu-wen Shi,
  • Rong-sheng Zhao,
  • Rong-sheng Zhao

DOI
https://doi.org/10.3389/fmed.2022.829267
Journal volume & issue
Vol. 9

Abstract

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Thrombocytopenia can cause substantial morbidity and mortality in critically ill patients. There are multiple etiology factors and various mechanisms associated with thrombocytopenia, of which drug-induced thrombocytopenia (DITP) deserves attention. Herein, we describe a case of severe thrombocytopenia during intensive care unit (ICU) hospitalization that was likely to be associated with vancomycin. By revealing the process of identifying this case of DITP and reviewing relevant clinical studies, a risk alert of vancomycin-related severe hematotoxicity should be considered.

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