Diagnostic Validity and Reliability of Low-Dose Prospective ECG-Triggering Cardiac CT in Preoperative Assessment of Complex Congenital Heart Diseases (CHDs)
Yassir Edrees Almalki,
Mohammad Abd Alkhalik Basha,
Sharifa Khalid Alduraibi,
Khalaf Alshamrani,
Mohammed Ayed Huneif,
Alaa Khalid Alduraibi,
Sultan A. Almedhesh,
Hassan A. Alshamrani,
Khaled Ahmed Ahmed Elbanna,
Youssef H. Algazzar,
Maha Ibrahim Metwally
Affiliations
Yassir Edrees Almalki
Division of Radiology, Department of Internal Medicine, Medical College, Najran University, Najran 61441, Saudi Arabia
Mohammad Abd Alkhalik Basha
Department of Diagnostic Radiology, Faculty of Human Medicine, Zagazig University, Zagazig 44519, Egypt
Sharifa Khalid Alduraibi
Department of Radiology, College of Medicine, Qassim University, Buraidah 52571, Saudi Arabia
Khalaf Alshamrani
Department of Radiological Science, College of Applied Medical Science, Najran University, Najran 61441, Saudi Arabia
Mohammed Ayed Huneif
Department of Pediatrics, College of Medicine, Najran University, Najran 61441, Saudi Arabia
Alaa Khalid Alduraibi
Department of Radiology, College of Medicine, Qassim University, Buraidah 52571, Saudi Arabia
Sultan A. Almedhesh
Department of Pediatrics, College of Medicine, Najran University, Najran 61441, Saudi Arabia
Hassan A. Alshamrani
Department of Radiological Science, College of Applied Medical Science, Najran University, Najran 61441, Saudi Arabia
Khaled Ahmed Ahmed Elbanna
Department of Internal Medicine, Faculty of Human Medicine, Zagazig University, Zagazig 44519, Egypt
Youssef H. Algazzar
Department of internal medicine, Katai Gabor hospital, 5300 Karcag, Hungary
Maha Ibrahim Metwally
Department of Diagnostic Radiology, Faculty of Human Medicine, Zagazig University, Zagazig 44519, Egypt
For the precise preoperative evaluation of complex congenital heart diseases (CHDs) with reduced radiation dose exposure, we assessed the diagnostic validity and reliability of low-dose prospective ECG-gated cardiac CT (CCT). Forty-two individuals with complex CHDs who underwent preoperative CCT as part of a prospective study were included. Each CCT image was examined independently by two radiologists. The primary reference for assessing the diagnostic validity of the CCT was the post-operative data. Infants and neonates were the most common age group suffering from complex CHDs. The mean volume of the CT dose index was 1.44 ± 0.47 mGy, the mean value of the dose-length product was 14.13 ± 5.4 mGy*cm, and the mean value of the effective radiation dose was 0.58 ± 0.13 mSv. The sensitivity, specificity, PPV, NPV, and accuracy of the low-dose prospective ECG-gated CCT for identifying complex CHDs were 95.6%, 98%, 97%, 97%, and 97% for reader 1 and 92.6%, 97%, 95.5%, 95.1%, and 95.2% for reader 2, respectively. The overall inter-reader agreement for interpreting the cardiac CCTs was good (κ = 0.74). According to the results of our investigation, low-dose prospective ECG-gated CCT is a useful and trustworthy method for assessing coronary arteries and making a precise preoperative diagnosis of complex CHDs.
