Annals of Internal Medicine: Clinical Cases (Sep 2022)

Muscular Polyarteritis Nodosa: A Case Series Study of 6 Patients

  • Fumitoshi Fukuzawa,
  • Kiyoshi Shikino,
  • Kosuke Ishizuka,
  • Yosuke Yamauchi,
  • Daiki Yokokawa,
  • Akiko Ikegami,
  • Takanori Uehara,
  • Masatomi Ikusaka

DOI
https://doi.org/10.7326/aimcc.2022.0179
Journal volume & issue
Vol. 1, no. 7

Abstract

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A subset of polyarteritis nodosa known as muscular polyarteritis nodosa (MPAN) is a disease process that remains mostly limited to the muscle. Here, we report 6 patient cases of MPAN for which we investigated the clinical features. We examined 6 patients who visited our department between April 2010 and October 2019 and had a confirmed diagnosis of MPAN. The clinical features of MPAN include fever, myalgia, muscle tenderness without restricted joint range of motion, elevated C-reactive protein levels, and normal creatine kinase levels. In the presence of such features, MPAN should be suspected and magnetic resonance imaging and biopsy be performed.