Nature Communications (Feb 2023)
CvkR is a MerR-type transcriptional repressor of class 2 type V-K CRISPR-associated transposase systems
Abstract
RNA-guided, CRISPR-associated transposons hold great promise for precision genome editing. Here, the authors provide genetic, biochemical and structural data how their activity is regulated in situ by CvkR, an unusual MerR family regulator.