Cell Death Discovery (Oct 2021)

MicroRNA in extracellular vesicles regulates inflammation through macrophages under hypoxia

  • Ye Li,
  • Jin Tan,
  • Yuyang Miao,
  • Qiang Zhang

DOI
https://doi.org/10.1038/s41420-021-00670-2
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 12

Abstract

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EV-miRNAs regulate the polarization phenotype of macrophages and promote the release of inflammation-related cytokines through a variety of signaling pathways under hypoxia, ultimately affect the development of inflammation.