Radiology Case Reports (Aug 2024)

Spontaneous thrombosis of a large unruptured intracranial aneurysm causing ischemic stroke due to occlusion of the parent artery: A case report and literature review

  • Ta Vuong Khoa, MD, PhD,
  • Truong Minh Thuong, MD,
  • Phan Xuan Quang, MD,
  • Tran Quyet Thang, MD,
  • Nguyen Nhut Linh, MD,
  • Pham-Thi Thu Ngan, MD,
  • Phan Dinh Van, MD,
  • Phi Ngoc Duong, MD,
  • Nguyen Minh Duc, MD

Journal volume & issue
Vol. 19, no. 8
pp. 3405 – 3410

Abstract

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Spontaneous thrombosis of an unruptured large or giant saccular intracranial aneurysm is a well-known phenomenon and can cause ischemic stroke (IS), which is a rare event. The possible pathogenic mechanisms of IS include distal embolic occlusion secondary to migration of the intra-aneurysmal thrombus, occlusion of the parent artery lumen caused by the retrograde extension of the aneurysmal thrombosis, external compression of the parent artery due to the increased aneurysmal mass effect. Among these, IS due to simultaneous thromboses of the aneurysm and its parent artery is extremely rare, with only a few cases reported in the literature. Herein, we present a case of a 18-year-old woman who suffered an acute IS, attribute to spontaneous complete thrombosis of an unruptured large saccular aneurysm of the right middle cerebral artery with occlusion of the parent artery, and we review the literature simultaneously.

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