Nature Communications (Oct 2021)
Sub-centrosomal mapping identifies augmin-γTuRC as part of a centriole-stabilizing scaffold
Abstract
The γ-tubulin ring complex (γTuRC) nucleates microtubules at the centrosome, but how this function is related to γTuRC subcentrosomal distribution is unclear. Here the authors show that γTuRC in the centriole lumen has a nucleation-independent role in centriole integrity and cilium assembly.