Allergy, Asthma & Clinical Immunology (Jul 2010)

HAE international home therapy consensus document

  • Longhurst Hilary J,
  • Farkas Henriette,
  • Craig Timothy,
  • Aygören-Pürsün Emel,
  • Bethune Claire,
  • Bjorkander Janne,
  • Bork Konrad,
  • Bouillet Laurence,
  • Boysen Henrik,
  • Bygum Anette,
  • Caballero Teresa,
  • Cicardi Marco,
  • Dempster John,
  • Gompels Mark,
  • Gooi Jimmy,
  • Grigoriadou Sofia,
  • Huffer Ursula,
  • Kreuz Wolfhart,
  • Levi Marcel M,
  • Long Janet,
  • Martinez-Saguer Inmaculada,
  • Raguet Michel,
  • Reshef Avner,
  • Bowen Tom,
  • Zuraw Bruce

DOI
https://doi.org/10.1186/1710-1492-6-22
Journal volume & issue
Vol. 6, no. 1
p. 22

Abstract

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Abstract Hereditary angioedema (C1 inhibitor deficiency, HAE) is associated with intermittent swellings which are disabling and may be fatal. Effective treatments are available and these are most useful when given early in the course of the swelling. The requirement to attend a medical facility for parenteral treatment results in delays. Home therapy offers the possibility of earlier treatment and better symptom control, enabling patients to live more healthy, productive lives. This paper examines the evidence for patient-controlled home treatment of acute attacks ('self or assisted administration') and suggests a framework for patients and physicians interested in participating in home or self-administration programmes. It represents the opinion of the authors who have a wide range of expert experience in the management of HAE.