The Importance of Keto-Enol Forms of Arylpropanoids Acting as Antifungal Compounds

Abstract

We report here the importance of a keto-enol equilibrium of an arylpropanoid series acting as antifungal agents. An interesting relationship between ln MIC, ∆E enolization and net atomic charges was found. Two compounds were synthesized and their MIC evaluated in order to prove the above relationship.

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