Osteology (May 2024)

Sociodemographic and Lifestyle Risk Factors Associated with Fragility Hip Fractures: A Systematic Review and Meta-Analysis

  • Diana Yeritsyan,
  • Kaveh Momenzadeh,
  • Amin Mohamadi,
  • Sharri J. Mortensen,
  • Indeevar R. Beeram,
  • Daniela Caro,
  • Nadim Kheir,
  • Megan McNichol,
  • John J. Wixted,
  • Paul Appleton,
  • Arvind von Keudell,
  • Ara Nazarian

DOI
https://doi.org/10.3390/osteology4020006
Journal volume & issue
Vol. 4, no. 2
pp. 64 – 87

Abstract

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Hip fractures inflict heightened morbidity and mortality upon older adults. Although previous studies have explored the impact of individual demographic factors on hip fracture risk, a comprehensive review can help reconcile disparities among these factors. This meta-analysis encompassed 69 studies involving 976,677 participants and 99,298 cases of hip fractures. We found that age ≥ 85 (OR = 1.75), BMI 30 (OR = 0.38), parity (OR = 0.79), non-Caucasian descent (overall OR = 0.4, Asian OR 0.36, Black OR = 0.39, and Hispanic OR = 0.45), and rural residence (OR = 0.95) were significantly associated with a diminished risk of hip fracture. Hip fracture patients exhibited significantly lower weight and BMI than the non-fracture group, while their age was significantly higher. However, age at menopause and height did not significantly differ between the two groups.

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