The role of cytokines in degenerative spine disorders

Abstract

Background: Degenerative spine disorders (DSD) are the most frequent reason of morbidity in adults. Commonly DSD includes degenerative disorders of intervertebral discs (IVDs), spinal stenosis and degenerative spondylolisthesis (SL). There is increasing evidence about significant role of cytokines in DSD pathogenesis, symptomathology and progression, but their protective levels remain still unknown.

Keywords

• degenerative lumbar spondylolisthesis
• herniated intervertebral disc
• cytokine levels
• annulus fibrosus
• nucleus pulposus