Бюллетень сибирской медицины (Dec 2012)

Levels of T-regulatory cells in patients with chronic obstructive pulmonary disease and basis therapy efficiency

  • N. A. Kirillova,
  • I. A. Deyev,
  • Ye. E. Kremer,
  • L. M. Ogorodova,
  • G. E. Chernogoryuk,
  • Ye. S. Kulikov,
  • S. V. Fedosenko

DOI
https://doi.org/10.20538/1682-0363-2012-6-153-159
Journal volume & issue
Vol. 11, no. 6
pp. 153 – 159

Abstract

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Open prospective comparative study was performed to evaluate association of basis treatment of chronic obstructive pulmonary disease (COPD) and initial levels of individual subpopulations of T-regulatory cells. Results of study suggested what high regulatory performance in COPD (CD4+FoxP3+ > 7%) associated with low effect of anti-inflammatory therapy. This findings may be taken into account at therapy appointment.

Keywords