Revista da Sociedade Brasileira de Medicina Tropical (Jul 2021)

Pre- and post-COVID-19 evaluation of antimicrobial susceptibility for healthcare-associated infections in the intensive care unit of a tertiary hospital

  • Gilberto Gambero Gaspar,
  • Lécio Rodrigues Ferreira,
  • Cinara Silva Feliciano,
  • Cláudio Penido Campos Júnior,
  • Fabiana Murad Rossin Molina,
  • Andrea Cristina Soares Vendruscolo,
  • Giovana Marcão Araújo Bradan,
  • Nátali Artal Padovani Lopes,
  • Roberto Martinez,
  • Valdes Roberto Bollela

DOI
https://doi.org/10.1590/0037-8682-0090-2021
Journal volume & issue
Vol. 54

Abstract

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Abstract INTRODUCTION: Antimicrobial resistance has worsened since the onset of COVID-19. METHODS: This study involved patients admitted to the adult intensive care unit (ICU) of a tertiary hospital. Pre- and post-COVID-19 data were analyzed. The healthcare-related infections (HCRIs) reported between January 2018 and January 2020 and during the pandemic between February and July 2020 were compared. RESULTS: Antimicrobial resistance increased during the pandemic, especially for Klebsiella pneumoniae isolates, with a rate increase from 5% to 50% for Polymyxin B. CONCLUSIONS: The susceptibilities of the main pathogens associated with HCRIs in the ICU changed and should be considered in managing severe COVID-19.

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