Nature Communications (Dec 2017)

Reading and editing the Pleurodeles waltl genome reveals novel features of tetrapod regeneration

  • Ahmed Elewa,
  • Heng Wang,
  • Carlos Talavera-López,
  • Alberto Joven,
  • Gonçalo Brito,
  • Anoop Kumar,
  • L. Shahul Hameed,
  • May Penrad-Mobayed,
  • Zeyu Yao,
  • Neda Zamani,
  • Yamen Abbas,
  • Ilgar Abdullayev,
  • Rickard Sandberg,
  • Manfred Grabherr,
  • Björn Andersson,
  • András Simon

DOI
https://doi.org/10.1038/s41467-017-01964-9
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 9

Abstract

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The Iberian ribbed newt Pleurodeles waltl has a wide spectrum of regeneration abilities. Here, Elewa et al. sequence its ~20 Gb genome and transcriptome to investigate the molecular features underlying its regenerative capacities.