1Federal Research Centre "Information and Management" of the Russian Academy of Sciences. 119333, Russian Federation, Moscow, ul. Vavilova, d. 40; 2Ivanovo State Medical Academy of the Ministry of Health of the Russian Federation. 153462, Russian Federation, Ivanovo, pr. Sheremetevskii, d. 8
I.Yu.Torshin
Federal Research Centre "Information and Management" of the Russian Academy of Sciences. 119333, Russian Federation, Moscow, ul. Vavilova, d. 40
D.E.Frolova
Ivanovo State Medical Academy of the Ministry of Health of the Russian Federation. 153462, Russian Federation, Ivanovo, pr. Sheremetevskii, d. 8
N.P.Lapochkina
Ivanovo State Medical Academy of the Ministry of Health of the Russian Federation. 153462, Russian Federation, Ivanovo, pr. Sheremetevskii, d. 8
A.N.Gromov
Federal Research Centre "Information and Management" of the Russian Academy of Sciences. 119333, Russian Federation, Moscow, ul. Vavilova, d. 40
Vitamin D is characterized by undeniable antitumor properties that are important for both prevention and treatment of tumor diseases. The results of a systematic analysis of the molecular mechanisms of antitumor effects of vitamin D (inhibition of the Wnt/b-catenin cascade, the transcription factor WSTF) and the results of clinical studies of patients with estrogen-dependent tumors are presented, indicating the promise of combined use of estrogen and vitamin D.