Гинекология (Jan 2018)

Vitamin D and estrogen-dependent tumors

  • O.A.Gromova,
  • I.Yu.Torshin,
  • D.E.Frolova,
  • N.P.Lapochkina,
  • A.N.Gromov

DOI
https://doi.org/10.26442/2079-5696_20.1.23-30
Journal volume & issue
Vol. 20, no. 1
pp. 23 – 30

Abstract

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Vitamin D is characterized by undeniable antitumor properties that are important for both prevention and treatment of tumor diseases. The results of a systematic analysis of the molecular mechanisms of antitumor effects of vitamin D (inhibition of the Wnt/b-catenin cascade, the transcription factor WSTF) and the results of clinical studies of patients with estrogen-dependent tumors are presented, indicating the promise of combined use of estrogen and vitamin D.

Keywords