Hypertension in Pregnancy (Jan 2020)

Maternal asthma and the risk of hypertensive disorders of pregnancy: a systematic review and meta-analysis of cohort studies

  • Meng Wang,
  • Wenbo He,
  • Meixuan Li,
  • Fuyun Li,
  • Lili Jiang,
  • Jiabin Wang,
  • Hui Wang,
  • Xudong Liu,
  • Kehu Yang,
  • Jie Qiu

DOI
https://doi.org/10.1080/10641955.2019.1693591
Journal volume & issue
Vol. 39, no. 1
pp. 12 – 24

Abstract

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Objective: The aim of this study was to demonstrate the association between maternal asthma and the risk of hypertensive disorders of pregnancy. Methods: A systematic search of seven databases was conducted. A meta-analysis was performed to calculate risk ratios and 95% CI using random-effects models. Results: Asthma was associated with an increased risk of pregnancy-induced hypertension (RR 1.45, 95%CI 1.29–1.63), transient hypertension of pregnancy (RR 2.00, 95%CI 1.52–2.63), preeclampsia or eclampsia (RR 1.28, 95%CI 1.25–1.32), preeclampsia (RR 1.43, 95%CI 1.31–1.57) and eclampsia (RR 1.56, 95%CI 1.13–2.15). Conclusion: The meta-analysis illustrated that asthma was significantly increased risk of hypertension during pregnancy.

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