Marine Drugs (Nov 2021)

Anti-Allergic Effect of Low Molecular Weight Digest from Abalone Viscera on Atopic Dermatitis-Induced NC/Nga

  • Tae-Hee Kim,
  • Seong-Yeong Heo,
  • Gun-Woo Oh,
  • Won Sun Park,
  • Il-Whan Choi,
  • Zhong-Ji Qian,
  • Won-Kyo Jung

DOI
https://doi.org/10.3390/md19110634
Journal volume & issue
Vol. 19, no. 11
p. 634

Abstract

Read online

Abalone viscera (AV) is one of the byproducts of the seafood processing industry. The low molecular weight (Dermatophagoides farinae. The results demonstrated that the LMW-AV reduced a number of clinical symptoms, such as the severity of the dermatitis and serum immunoglobulin E levels. Moreover, LMW-AV could inhibit the expression of chemokines and cytokines. The histological analysis indicated that the LMW-AV has suppressed the eosinophil count and the mast cell infiltration into the upper dermis. The results suggest that LMW-AV can be considered as a promising candidate for AD treatment.

Keywords