Saudi Pharmaceutical Journal (May 2016)

Research on AIDS patients’ survival time after highly active antiretroviral therapy, treatment effect and treatment modes

  • Riying Lv,
  • Guojian Li,
  • Jizhou Wu,
  • Yujia Zhu,
  • Xionglin Qin,
  • Shixiong Li

DOI
https://doi.org/10.1016/j.jsps.2016.04.004
Journal volume & issue
Vol. 24, no. 3
pp. 318 – 321

Abstract

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To fully define clinical efficacy of highly active antiretroviral therapy for AIDS, analyze patients’ survival time and treatment mode after receiving treatment, and provide scientific theory to guide improvement of antiviral therapy, this paper selected 3100 cases of patients diagnosed with AIDS during April 2006 and April 2014 as object of this study. All patients were treated with highly active antiretroviral therapy. The main analysis contents of this study include CD4 + T lymphocyte count, viral load changes, incidence of opportunistic infections, specific cause of death and the like. The results show that patients’ CD4 + T lymphocyte levels are significantly increased 3, 18, and 24 months after treatment, difference between the situation after and before receiving treatment, P < 0.05, with statistically significant difference. Analyzed from effective inhibition of virus, effective inhibition rate is 72.58.0% (2250/3100). Main causes of death in patients is usually respiratory failure. It thus can be concluded that highly active antiretroviral therapy for AIDS is with good clinical effect, which can effectively improve survival time of patients. So it enjoys application value of being widely used in clinical treatment of AIDS.

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