Nature Communications (Dec 2020)
A collection of bacterial isolates from the pig intestine reveals functional and taxonomic diversity
- David Wylensek,
- Thomas C. A. Hitch,
- Thomas Riedel,
- Afrizal Afrizal,
- Neeraj Kumar,
- Esther Wortmann,
- Tianzhe Liu,
- Saravanan Devendran,
- Till R. Lesker,
- Sara B. Hernández,
- Viktoria Heine,
- Eva M. Buhl,
- Paul M. D’Agostino,
- Fabio Cumbo,
- Thomas Fischöder,
- Marzena Wyschkon,
- Torey Looft,
- Valeria R. Parreira,
- Birte Abt,
- Heidi L. Doden,
- Lindsey Ly,
- João M. P. Alves,
- Markus Reichlin,
- Krzysztof Flisikowski,
- Laura Navarro Suarez,
- Anthony P. Neumann,
- Garret Suen,
- Tomas de Wouters,
- Sascha Rohn,
- Ilias Lagkouvardos,
- Emma Allen-Vercoe,
- Cathrin Spröer,
- Boyke Bunk,
- Anja J. Taverne-Thiele,
- Marcel Giesbers,
- Jerry M. Wells,
- Klaus Neuhaus,
- Angelika Schnieke,
- Felipe Cava,
- Nicola Segata,
- Lothar Elling,
- Till Strowig,
- Jason M. Ridlon,
- Tobias A. M. Gulder,
- Jörg Overmann,
- Thomas Clavel
Affiliations
- David Wylensek
- Functional Microbiome Research Group, RWTH University Hospital
- Thomas C. A. Hitch
- Functional Microbiome Research Group, RWTH University Hospital
- Thomas Riedel
- Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures
- Afrizal Afrizal
- Functional Microbiome Research Group, RWTH University Hospital
- Neeraj Kumar
- Functional Microbiome Research Group, RWTH University Hospital
- Esther Wortmann
- Functional Microbiome Research Group, RWTH University Hospital
- Tianzhe Liu
- Chair of Technical Biochemistry, Technical University of Dresden
- Saravanan Devendran
- Microbiome Metabolic Engineering Theme, Carl R. Woese Institute for Genomic Biology
- Till R. Lesker
- Department of Microbial Immune Regulation, Helmholtz Centre for Infection Research
- Sara B. Hernández
- Laboratory for Molecular Infection Medicine Sweden (MIMS), Department of Molecular Biology, Umeå University
- Viktoria Heine
- Laboratory for Biomaterials, Institute for Biotechnology and Helmholtz-Institute for Biomedical Engineering, RWTH Aachen University
- Eva M. Buhl
- Electron Microscopy Facility, Institute of Pathology, RWTH University Hospital
- Paul M. D’Agostino
- Chair of Technical Biochemistry, Technical University of Dresden
- Fabio Cumbo
- Department CIBIO, University of Trento
- Thomas Fischöder
- Laboratory for Biomaterials, Institute for Biotechnology and Helmholtz-Institute for Biomedical Engineering, RWTH Aachen University
- Marzena Wyschkon
- Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures
- Torey Looft
- National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture
- Valeria R. Parreira
- Department of Molecular and Cellular Biology, University of Guelph
- Birte Abt
- Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures
- Heidi L. Doden
- Microbiome Metabolic Engineering Theme, Carl R. Woese Institute for Genomic Biology
- Lindsey Ly
- Microbiome Metabolic Engineering Theme, Carl R. Woese Institute for Genomic Biology
- João M. P. Alves
- Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo
- Markus Reichlin
- PharmaBiome AG
- Krzysztof Flisikowski
- Chair of Livestock Biotechnology, Weihenstephan School of Life Science, Technical University of Munich
- Laura Navarro Suarez
- Institute of Food Chemistry, Hamburg School of Food Science, University of Hamburg
- Anthony P. Neumann
- Department of Bacteriology, University of Wisconsin-Madison
- Garret Suen
- Department of Bacteriology, University of Wisconsin-Madison
- Tomas de Wouters
- PharmaBiome AG
- Sascha Rohn
- Institute of Food Chemistry, Hamburg School of Food Science, University of Hamburg
- Ilias Lagkouvardos
- ZIEL - Institute for Food & Health, Technical University of Munich
- Emma Allen-Vercoe
- Department of Molecular and Cellular Biology, University of Guelph
- Cathrin Spröer
- Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures
- Boyke Bunk
- Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures
- Anja J. Taverne-Thiele
- Host-Microbe Interactomics Group, Department of Animal Science, Wageningen University
- Marcel Giesbers
- Electron Microscopy Center, Wageningen University
- Jerry M. Wells
- Host-Microbe Interactomics Group, Department of Animal Science, Wageningen University
- Klaus Neuhaus
- ZIEL - Institute for Food & Health, Technical University of Munich
- Angelika Schnieke
- ZIEL - Institute for Food & Health, Technical University of Munich
- Felipe Cava
- Laboratory for Molecular Infection Medicine Sweden (MIMS), Department of Molecular Biology, Umeå University
- Nicola Segata
- Department CIBIO, University of Trento
- Lothar Elling
- Laboratory for Biomaterials, Institute for Biotechnology and Helmholtz-Institute for Biomedical Engineering, RWTH Aachen University
- Till Strowig
- Department of Microbial Immune Regulation, Helmholtz Centre for Infection Research
- Jason M. Ridlon
- Microbiome Metabolic Engineering Theme, Carl R. Woese Institute for Genomic Biology
- Tobias A. M. Gulder
- Chair of Technical Biochemistry, Technical University of Dresden
- Jörg Overmann
- Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures
- Thomas Clavel
- Functional Microbiome Research Group, RWTH University Hospital
- DOI
- https://doi.org/10.1038/s41467-020-19929-w
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 26
Abstract
The authors present a public collection of 117 bacterial isolates from the pig gut, including the description of 38 novel taxa. Interesting functions discovered in these organisms include a new fucosyltransferease and sactipeptide-like molecules encoded by biosynthetic gene clusters.
