Role of various types of viruses in development of early aged Breast Cancer: A brief review

Abstract

World widely, Breast cancer is the most common type of cancer amongst women. External and internal factors both are responsible for beginning, advancement and development of breast cancer and from many studies it is well known that environmental elements have a significant effect in etiology of breast cancer. When it comes to environmental factors, effects of viruses are of great concern. Virus-associated cancer brings up a cancer in which the malicious conversion of the host’s diseased cells results due to any viral infection. Until now it has learned that human papillomaviruses (HPV), Epstein–Barr (EBV) and mouse mammary tumor virus (MMTV) are the prime candidate viruses that act as agents of causing breast cancer. The initiator is only one in a sequence of steps essential for malignant cells development. Breast cancer could be a hereditary disease but it is expected to account for a very small percentage of breast cancer cases. From this idea it is obvious that there should be more efforts required in evaluating the role of viruses in carcinogenesis that could be characterized by further confounding and synergistic special effects of carcinogenic aspects still exact role of viruses in tumorigenesis is unclear, but it seem like that these are responsible for causing the disease.

Keywords

• tumerogenesis
• breast cancer
• human papillomaviruses
• epstein–barr
• mouse mammary tumor virus