Nature Communications (Dec 2019)
Profiling of the plasma proteome across different stages of human heart failure
- Anna Egerstedt,
- John Berntsson,
- Maya Landenhed Smith,
- Olof Gidlöf,
- Roland Nilsson,
- Mark Benson,
- Quinn S. Wells,
- Selvi Celik,
- Carl Lejonberg,
- Laurie Farrell,
- Sumita Sinha,
- Dongxiao Shen,
- Jakob Lundgren,
- Göran Rådegran,
- Debby Ngo,
- Gunnar Engström,
- Qiong Yang,
- Thomas J. Wang,
- Robert E. Gerszten,
- J. Gustav Smith
Affiliations
- Anna Egerstedt
- Department of Cardiology, Clinical Sciences, Lund University
- John Berntsson
- Department of Cardiology, Clinical Sciences, Lund University
- Maya Landenhed Smith
- Department of Cardiothoracic Surgery, Clinical Sciences, Lund University and Skåne University Hospital
- Olof Gidlöf
- Department of Cardiology, Clinical Sciences, Lund University
- Roland Nilsson
- Department of Medicine, Karolinska Institutet and Karolinska University Hospital
- Mark Benson
- Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School
- Quinn S. Wells
- Division of Cardiovascular Medicine, Vanderbilt University
- Selvi Celik
- Department of Cardiology, Clinical Sciences, Lund University
- Carl Lejonberg
- Department of Cardiology, Clinical Sciences, Lund University
- Laurie Farrell
- Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School
- Sumita Sinha
- Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School
- Dongxiao Shen
- Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School
- Jakob Lundgren
- Department of Cardiology, Clinical Sciences, Lund University
- Göran Rådegran
- Department of Cardiology, Clinical Sciences, Lund University
- Debby Ngo
- Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School
- Gunnar Engström
- Cardiovascular Epidemiology, Clinical Sciences, Lund University
- Qiong Yang
- Department of Biostatistics, Boston University School of Public Health
- Thomas J. Wang
- Division of Cardiovascular Medicine, Vanderbilt University
- Robert E. Gerszten
- Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School
- J. Gustav Smith
- Department of Cardiology, Clinical Sciences, Lund University
- DOI
- https://doi.org/10.1038/s41467-019-13306-y
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 13
Abstract
Heart failure is a major health issue worldwide. Here, Egerstedt et al. perform proteomic profiling of human plasma at different stages of heart failure, providing a comprehensive analysis of changes in the plasma proteome during disease progression.
