Biosynthesis of Macrocyclic Peptides with C‑Terminal β‑Amino-α-keto Acid Groups by Three Different Metalloenzymes

• Dinh T. Nguyen,
• Lingyang Zhu,
• Danielle L. Gray,
• Toby J. Woods,
• Chandrashekhar Padhi,
• Kristen M. Flatt,
• Douglas A. Mitchell,
• Wilfred A. van der Donk

Affiliations

Dinh T. Nguyen

†Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States

Lingyang Zhu

School of Chemical Sciences NMR Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States

Danielle L. Gray

School of Chemical Sciences George L. Clark X-Ray Facility and 3M Materials Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States

Toby J. Woods

School of Chemical Sciences George L. Clark X-Ray Facility and 3M Materials Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States

Chandrashekhar Padhi

†Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States

Kristen M. Flatt

Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States

Douglas A. Mitchell

†Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States

Wilfred A. van der Donk

†Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States