Southern African Journal of HIV Medicine (Jun 2013)

Progressive HIV infection in the presence of a raised CD4+ count: HIV/HTLV-1 co-infection

  • Ahmad Farid Haeri Mazanderani,
  • Osman Ebrahim

DOI
https://doi.org/10.4102/sajhivmed.v14i2.85
Journal volume & issue
Vol. 14, no. 2
pp. 92 – 94

Abstract

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There are a number of pathophysiological causes for a normal or raised CD4 count in the context of progressive HIV infection. These include various co-infections, previous splenectomy, and lymphoproliferative disorders. Such circumstances can both confound HIV diagnosis and delay initiation of chemoprophylaxis and highly active antiretroviral therapy (HAART). We describe the case of a patient co-infected with HIV and human T-cell lymphotropic virus type 1 (HTLV-1) who, prior to HAART initiation, was found to have progressive immune deficiency associated with a raised CD4 count.

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