European Journal of Hybrid Imaging (Sep 2022)

Foreign body-type giant cell reaction with extensive granulation tissue and intense inflammation after chemotherapy mimicking residual lymphoma on FDG PET

  • Sakib Kazi,
  • Stavros Raptis,
  • Farzad Abbaspour,
  • Wanzhen Zeng

DOI
https://doi.org/10.1186/s41824-022-00137-2
Journal volume & issue
Vol. 6, no. 1
pp. 1 – 6

Abstract

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Abstract Foreign body-type giant cell reaction is typically a biological and immunological reaction to the presence of foreign bodies such as catheters, parasites or biomaterials with a collection of fused macrophages (giant cell). We reported an unusual case of [18F]FDG PET findings in diffuse large B cell lymphoma in the urinary bladder following incomplete resection and chemotherapy. As the restaging [18F]FDG PET showed intense [18F]FDG uptake in the urinary bladder at the resection site concerning for recurrence, the lesion was subsequently resected and histopathology showed extensive granulation tissue with foreign body-type giant cell reaction with no suspected foreign bodies or neoplasia.

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