Two new compounds from leaves of Capparis dongvanensis (Sy, B. H. Quang & D. V. Hai) and inhibition activities

Abstract

In continuation of the research, the phytochemical investigation of Capparis dongvanensis (Sy, B. H. Quang & D. V. Hai) (Capparaceae). In this work, we described the isolation and identification of two novel polycyclic compounds Capparisone A (1) and Capparisone B (2). The structures of these compounds were determined based on NMR spectral data and mass spectrometry. Furthermore, we evaluated the inhibitory activities of isolated compounds from C. dongvanensis leaves against five cancer cell lines, the results showed that isolated compounds exhibited good activities on four cancer cell lines. Otherwise, two isolated compounds 1 and 2 and EA extract also exhibited the anti-oxidant activity in the DPPH free radical scavenging assay.

Keywords

• capparis dongvanensis
• vietnam
• anti-cancer activity
• lao cai
• capparis