Four New Jacaranone Analogs from the Fruits of a Beibu Gulf Mangrove Avicennia marina

Abstract

Four new jacaranone analogs, marinoids F–I (1–4), were isolated from the fruits of a Beibu Gulf mangrove Avicennia marina. The structures were elucidated based on analysis of spectroscopic data. Marinoids F and G are shown to be diastereoisomers of chlorocornoside, a new halogen containing marine secondary metabolite. The antioxidant activity of the isolates was evaluated using a cellular antioxidant assay, and 4 showed good antioxidant activity (EC50 = 26 μM).

Keywords

• antioxidant
• Avicennia marina
• chlorocornoside
• cornoside
• jacaranone analogs
• marinoid