Clinical practice guideline recommendations for pediatric injury care: protocol for a systematic review
Alison Macpherson,
Belinda J Gabbe,
Henry Thomas Stelfox,
Roger Zemek,
Suzanne Beno,
Ian Pike,
François Lauzier,
Isabelle J Gagnon,
Pier-Alexandre Tardif,
Lynne Moore,
Alexis F Turgeon,
Matthew Weiss,
Mélanie Bérubé,
Antonia Stang,
Terry Klassen,
Emilie Beaulieu,
Simon Berthelot,
Marianne Beaudin,
Natalie Yanchar,
Gabrielle Freire,
Anis Ben Abdeljelil,
Eunice Gnanvi,
Sasha Carsen,
Melanie Labrosse
Affiliations
Alison Macpherson
ICES, Toronto, Ontario, Canada
Belinda J Gabbe
School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia
Henry Thomas Stelfox
Departments of Critical Care Medicine, Medicine and Community Health Sciences, O’Brien Institute for Public Health, University of Calgary, Calgary, Alberta, Canada
Roger Zemek
2University of Ottawa, Ottawa, Canada
Suzanne Beno
Division of Emergency Medicine, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
Ian Pike
1BC Injury Research and Prevention Unit, BC Children’s Hospital Research Institute
François Lauzier
Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, Faculté de médecine, Université Laval, Quebec City, Québec, Canada
Isabelle J Gagnon
Division of Pediatric Emergency Medicine, McGill University Health Centre, Montreal Children’s Hospital, Montreal, Quebec, Canada
Pier-Alexandre Tardif
Population Health and Optimal Health Practices Research Unit, Trauma – Emergency – Critical Care Medicine, Centre de Recherche du CHU de Québec (Hôpital de l’Enfant-Jésus), Université Laval, Québec City, Québec, Canada
Lynne Moore
Department of Social and Preventive Medicine, Faculté de médecine, Université Laval, Quebec City, Quebec, Canada
Alexis F Turgeon
Population Health and Optimal Health Practives Research Unit (Trauma - Emergency - Critical Care Medicine), Centre de Recherche du CHU de Québec - Université Laval, Quebec, Quebec, Canada
Matthew Weiss
Transplant Québec, Montreal, Québec, Canada
Mélanie Bérubé
Population Health and Optimal Practices Research Unit Research Unit (Trauma–Emergency–Critical Care Medicine), CHU de Québec-Université Laval Research Centre, Québec, Quebec, Canada
Antonia Stang
Pediatrics, Emergency Medicine, and Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
Terry Klassen
George & Fay Yee Centre for Health Care Innovation, Children’s Hospital Research Institute of Manitoba, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada
Emilie Beaulieu
Department of Pediatrics, Université Laval, Québec City, Québec, Canada
Simon Berthelot
7 VITAM - Centre de recherche en santé durable, Université Laval, Québec, Québec, Canada
Marianne Beaudin
Sainte-Justine Hospital, Department of Paediatric Surgery, Université de Montréal, Montreal, Quebec, Canada
Natalie Yanchar
Department of Surgery, University of Calgary, Calgary, Alberta, Canada
Gabrielle Freire
Division of Emergency Medicine, Department of Paediatrics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Anis Ben Abdeljelil
Population Health and Optimal Health Practices Research Unit, Trauma – Emergency – Critical Care Medicine, Centre de Recherche du CHU de Québec (Hôpital de l’Enfant-Jésus), Université Laval, Québec City, Québec, Canada
Eunice Gnanvi
Population Health and Optimal Health Practices Research Unit, Trauma – Emergency – Critical Care Medicine, Centre de Recherche du CHU de Québec (Hôpital de l’Enfant-Jésus), Université Laval, Québec City, Québec, Canada
Sasha Carsen
2Lund University, Lund, Sweden
Melanie Labrosse
Department of Pediatrics, Division of Emergency Medicine, CHU Sainte-Justine, Université de Montréal, Montreal, Quebec, Canada
Introduction Evidence suggests the presence of deficiencies in the quality of care provided to up to half of all paediatric trauma patients in Canada, the USA and Australia. Lack of adherence to evidence-based recommendations may be driven by lack of knowledge of clinical practice guidelines (CPGs), heterogeneity in recommendations or concerns about their quality. We aim to systematically review CPG recommendations for paediatric injury care and appraise their quality.Methods and analysis We will identify CPG recommendations through a comprehensive search strategy including Medical Literature Analysis and Retrieval System Online, Excerpta Medica dataBASE, Cochrane library, Web of Science, ClinicalTrials and websites of organisations publishing recommendations on paediatric injury care. We will consider CPGs including at least one recommendation targeting paediatric injury populations on any diagnostic or therapeutic intervention from the acute phase of care with any comparator developed in high-income countries in the last 15 years (January 2007 to a maximum of 6 months prior to submission). Pairs of reviewers will independently screen titles, abstracts and full text of eligible articles, extract data and evaluate the quality of CPGs and their recommendations using Appraisal of Guidelines Research and Evaluation (AGREE) II and AGREE Recommendations Excellence instruments, respectively. We will synthesise evidence on recommendations using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Evidence-to-Decision framework and present results within a recommendations matrix.Ethics and dissemination Ethics approval is not a requirement as this study is based on available published data. The results of this systematic review will be published in a peer-reviewed journal, presented at international scientific meetings and distributed to healthcare providers.PROSPERO registration number International Prospective Register of Systematic Reviews (CRD42021226934).
