Data regarding M1 muscarinic receptor-mediated modulation of hepatic catalase activity in response to oxidative stress

Ravirajsinh N. Jadeja; Nathalie H. Urrunaga; Daniel Ahmad; Sandeep Khurana

Data in Brief (Mar 2016)

Data regarding M1 muscarinic receptor-mediated modulation of hepatic catalase activity in response to oxidative stress

Ravirajsinh N. Jadeja,
Nathalie H. Urrunaga,
Daniel Ahmad,
Sandeep Khurana

Affiliations

Ravirajsinh N. Jadeja: Division of Gastroenterology and Hepatology, Medical College of Georgia, Augusta, GA 30912, USA
Nathalie H. Urrunaga: Division of Gastroenterology and Hepatology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Daniel Ahmad: Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Sandeep Khurana: Division of Gastroenterology and Hepatology, Medical College of Georgia, Augusta, GA 30912, USA; Corresponding author.

Journal volume & issue: Vol. 6
pp. 405 – 409

Abstract

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We recently demonstrated the role of M1 muscarinic receptors (M1R) in modulating oxidative stress in liver and hepatocytes (Urrunaga et al., 2015) [1]. Here we provide data regarding the effect of a novel M1R agonist, VU0357017 (Lebois et al., 2010) [2], on H2O2-mediated hepatocyte injury, the effect of an M1R antagonist VU0255035 (Sheffler et al., 2009) [3] on catalase and super oxide dismutase (SOD) activities in H2O2–treated hepatocytes in vitro, and finally, the effect of M1R ablation on hepatic catalase activity in acetaminophen (APAP)-treated mice. Keywords: Muscarinic receptors, Oxidative stress, Catalase

Published in Data in Brief

ISSN: 2352-3409 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Computer applications to medicine. Medical informatics; Science: Science (General)
Website: http://www.journals.elsevier.com/data-in-brief/

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