Obstetric and perinatal outcomes of dizygotic twin pregnancies resulting from in vitro fertilization versus spontaneous conception: a retrospective study
Hua Chen,
Ying Wan,
Haitao Xi,
Weijue Su,
Jing Cheng,
Chunfang Zhu,
Jieqiang Lv,
Xinmei Wu,
Junzhao Zhao
Affiliations
Hua Chen
Reproductive Center, Department of Obstetrics and Gynecology, The 2nd Affliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, China
Ying Wan
Department of Obstetrics and Gynecology, Jiaxing Maternal and Child Health-care Hospital, Jiaxing, China
Haitao Xi
Reproductive Center, Department of Obstetrics and Gynecology, The 2nd Affliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, China
Weijue Su
Wenzhou Medical University, Wenzhou, China
Jing Cheng
Reproductive Center, Department of Obstetrics and Gynecology, The 2nd Affliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, China
Chunfang Zhu
Reproductive Center, Department of Obstetrics and Gynecology, The 2nd Affliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, China
Jieqiang Lv
Reproductive Center, Department of Obstetrics and Gynecology, The 2nd Affliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, China
Xinmei Wu
Department of Clinical Laboratory, The 2nd Affliated Hospital & Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, China
Junzhao Zhao
Reproductive Center, Department of Obstetrics and Gynecology, The 2nd Affliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, China
This study was designed to to assess perinatal and neonatal outcomes of dizygotic twin pregnancies conceived naturally or by in vitro fertilization (IVF). After strict selection, the study included 470 dizygotic twin pregnancies. There were 249 resulting from IVF treatments and 221 conceiving spontaneously. After adjusting maternal age and primiparity, the results showed that there were no significant differences between the two groups (P > 0.05) in terms of maternal antenatal complications and neonatal outcomes. In conclusion, our study does not reveal increased risks for pregnancy-related complications and adverse neonatal outcomes in dizygotic twin pregnancies following IVF treatments. With these fundamental data, this study could provide a reference for perinatal care and clinical assisted reproductive technology (ART) treatment and help to inform infertile parents about the potential risks of IVF treatments.
