Magnetic molecularly imprinted polymers using ternary deep eutectic solvent as novel functional monomer for hydroxytyrosol separation
Xiaojing Wang,
Mengru Wang,
Bailin Wu,
Shengyuan Yu,
Zaizhi Liu,
Xuyang Qin,
Huijuan Xu,
Wei Li,
Sha Luo,
Lijuan Wang,
Chunhui Ma,
Shouxin Liu
Affiliations
Xiaojing Wang
Key Laboratory of Bio-based Material Science and Technology (Ministry of Education), College of Material Science and Engineering, Northeast Forestry University, 150040, Harbin, China
Mengru Wang
Key Laboratory of Bio-based Material Science and Technology (Ministry of Education), College of Material Science and Engineering, Northeast Forestry University, 150040, Harbin, China
Bailin Wu
Key Laboratory of Bio-based Material Science and Technology (Ministry of Education), College of Material Science and Engineering, Northeast Forestry University, 150040, Harbin, China
Shengyuan Yu
Key Laboratory of Bio-based Material Science and Technology (Ministry of Education), College of Material Science and Engineering, Northeast Forestry University, 150040, Harbin, China
Zaizhi Liu
College of Life Sciences, Jiangxi Normal University, 330022, Nanchang, China
Xuyang Qin
Key Laboratory of Bio-based Material Science and Technology (Ministry of Education), College of Material Science and Engineering, Northeast Forestry University, 150040, Harbin, China
Huijuan Xu
Key Laboratory of Bio-based Material Science and Technology (Ministry of Education), College of Material Science and Engineering, Northeast Forestry University, 150040, Harbin, China
Wei Li
Key Laboratory of Bio-based Material Science and Technology (Ministry of Education), College of Material Science and Engineering, Northeast Forestry University, 150040, Harbin, China
Sha Luo
Key Laboratory of Bio-based Material Science and Technology (Ministry of Education), College of Material Science and Engineering, Northeast Forestry University, 150040, Harbin, China
Lijuan Wang
Key Laboratory of Bio-based Material Science and Technology (Ministry of Education), College of Material Science and Engineering, Northeast Forestry University, 150040, Harbin, China
Chunhui Ma
Key Laboratory of Bio-based Material Science and Technology (Ministry of Education), College of Material Science and Engineering, Northeast Forestry University, 150040, Harbin, China; Corresponding author. Key Laboratory of Bio-based Material Science and Technology (Ministry of Education), College of Material Science and Engineering, Northeast Forestry University, Harbin, 150040, China.
Shouxin Liu
Key Laboratory of Bio-based Material Science and Technology (Ministry of Education), College of Material Science and Engineering, Northeast Forestry University, 150040, Harbin, China; Corresponding author. Key Laboratory of Bio-based Material Science and Technology (Ministry of Education), College of Material Science and Engineering, Northeast Forestry University, Harbin, 150040, China.
In this work, magnetic molecularly imprinted polymers (MIPs) for specific recognition of Hydroxytyrosol (HT) were designed by vinyl-modified magnetic particles (Fe3O4@SiO2@VTEOs) as carrier, ternary deep eutectic solvent (DES) as functional monomer, while ethylene glycol dimethacrylate (EGDMA) as crosslinker. The optimum amount of DES was obtained by adsorption experiments (molar ratio, caffeic acid: choline chloride: formic acid = 1:6:3) which were 140 μL in total. Under the optimized amount of DES, the maximum adsorption capacity of the MIPs particles was 42.43 mg g−1, which was superior to non-imprinted polymer (4.64 mg g−1) and the imprinting factor (IF) is 9.10. Syringin and Oleuropicrin were used as two reference molecules to test the selectivity of the DES-MIPs particles. The adsorption capacity of HT was 40.11 mg g−1. Three repeated experiments show that the polymer has high stability and repeatability (RSD = 5.50).
