Kerala Journal of Ophthalmology (Jan 2017)

Blue sclera and osteogenesis imperfecta - A rare association

  • Sujit Das,
  • Kavita Bhatnagar

DOI
https://doi.org/10.4103/kjo.kjo_75_17
Journal volume & issue
Vol. 29, no. 3
pp. 240 – 243

Abstract

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The sclera is a dense poorly vascularized connective tissue structure composed of Types I, III, IV, V, VI, and VIII collagen. The characteristic blue sclera is caused by thinness and transparency of the collagen fibers of the sclera that allow visualization of the underlying uvea. The sclera may be thinned in congenital diseases such as osteogenesis imperfecta or in acquired diseases such as iron deficiency anemia.

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