THE CONTENT OF NITROGEN OXIDE METABOLITES IN BLOOD AND GASTRIC JUICE OF CHILDREN SUFFERING FROM CHRONIC GASTRODUODENITIS

Abstract

48 children with chronic gastroduodenitis aged 9–16 were studied. There was an increased content of nitrogen monoxide derivatives in the blood of gastroduodenitis patients as compared with healthy ones. The increase of nitritebanions concentration is related to H. pylori infection. The increased level of nitrogen monooxide is a defensive reaction of the body to H. pylori persistence. The increased production of nitrogen oxide metabolites leads to an increasing acidity of the gastric juice. A direct link between an increased production nitrogen oxide metabolites and increased acidity of the gastric juice was established.Key words: chronic gastroduodenitis, children, nitriteanions, nitric oxide.