Nature Communications (Apr 2022)
Defining the early stages of intestinal colonisation by whipworms
- María A. Duque-Correa,
- David Goulding,
- Faye H. Rodgers,
- J. Andrew Gillis,
- Claire Cormie,
- Kate A. Rawlinson,
- Allison J. Bancroft,
- Hayley M. Bennett,
- Magda E. Lotkowska,
- Adam J. Reid,
- Anneliese O. Speak,
- Paul Scott,
- Nicholas Redshaw,
- Charlotte Tolley,
- Catherine McCarthy,
- Cordelia Brandt,
- Catherine Sharpe,
- Caroline Ridley,
- Judit Gali Moya,
- Claudia M. Carneiro,
- Tobias Starborg,
- Kelly S. Hayes,
- Nancy Holroyd,
- Mandy Sanders,
- David J. Thornton,
- Richard K. Grencis,
- Matthew Berriman
Affiliations
- María A. Duque-Correa
- Wellcome Sanger Institute, Wellcome Genome Campus
- David Goulding
- Wellcome Sanger Institute, Wellcome Genome Campus
- Faye H. Rodgers
- Wellcome Sanger Institute, Wellcome Genome Campus
- J. Andrew Gillis
- Department of Zoology, University of Cambridge
- Claire Cormie
- Wellcome Sanger Institute, Wellcome Genome Campus
- Kate A. Rawlinson
- Wellcome Sanger Institute, Wellcome Genome Campus
- Allison J. Bancroft
- Lydia Becker Institute of Immunology and Inflammation, Wellcome Trust Centre for Cell Matrix Research and Faculty of Biology, Medicine and Health, University of Manchester
- Hayley M. Bennett
- Wellcome Sanger Institute, Wellcome Genome Campus
- Magda E. Lotkowska
- Wellcome Sanger Institute, Wellcome Genome Campus
- Adam J. Reid
- Wellcome Sanger Institute, Wellcome Genome Campus
- Anneliese O. Speak
- Wellcome Sanger Institute, Wellcome Genome Campus
- Paul Scott
- Wellcome Sanger Institute, Wellcome Genome Campus
- Nicholas Redshaw
- Wellcome Sanger Institute, Wellcome Genome Campus
- Charlotte Tolley
- Wellcome Sanger Institute, Wellcome Genome Campus
- Catherine McCarthy
- Wellcome Sanger Institute, Wellcome Genome Campus
- Cordelia Brandt
- Wellcome Sanger Institute, Wellcome Genome Campus
- Catherine Sharpe
- Lydia Becker Institute of Immunology and Inflammation, Wellcome Trust Centre for Cell Matrix Research and Faculty of Biology, Medicine and Health, University of Manchester
- Caroline Ridley
- Lydia Becker Institute of Immunology and Inflammation, Wellcome Trust Centre for Cell Matrix Research and Faculty of Biology, Medicine and Health, University of Manchester
- Judit Gali Moya
- Faculty of Biology, University of Barcelona
- Claudia M. Carneiro
- Immunopathology Laboratory, NUPEB, Federal University of Ouro Preto, Campus Universitario Morro do Cruzeiro
- Tobias Starborg
- Lydia Becker Institute of Immunology and Inflammation, Wellcome Trust Centre for Cell Matrix Research and Faculty of Biology, Medicine and Health, University of Manchester
- Kelly S. Hayes
- Lydia Becker Institute of Immunology and Inflammation, Wellcome Trust Centre for Cell Matrix Research and Faculty of Biology, Medicine and Health, University of Manchester
- Nancy Holroyd
- Wellcome Sanger Institute, Wellcome Genome Campus
- Mandy Sanders
- Wellcome Sanger Institute, Wellcome Genome Campus
- David J. Thornton
- Lydia Becker Institute of Immunology and Inflammation, Wellcome Trust Centre for Cell Matrix Research and Faculty of Biology, Medicine and Health, University of Manchester
- Richard K. Grencis
- Lydia Becker Institute of Immunology and Inflammation, Wellcome Trust Centre for Cell Matrix Research and Faculty of Biology, Medicine and Health, University of Manchester
- Matthew Berriman
- Wellcome Sanger Institute, Wellcome Genome Campus
- DOI
- https://doi.org/10.1038/s41467-022-29334-0
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 15
Abstract
Whipworms are large parasites causing chronic disease in humans and other mammals. Here, the authors show how larvae create tunnels inside the gut lining and reveal the early host response to infection via Isg15 in mice and murine caecaloids.
