Progress of phosphorylated proteomics in breast cancer

Abstract

With the development of genomics, proteomics and transcriptomics, tumor research is becoming more and more systematic and in-depth. Compared with the genome, the proteome is more complex, more active and closer to the essence of life. Post-translational modification of proteins is a hot topic in proteomics, among which phosphorylation is the most common and widely studied. With the rapid development of proteomics technology, the application of proteomics to the discovery of specific markers of malignant tumors, the establishment of diagnostic models of proteins, treatment and prognosis, drug resistance and other aspects of the study gradually increased. This article reviewed the progress of phosphorylated proteomics in breast cancer.

Keywords

• phosphorylated proteomics
• breast cancer
• carcinogenesis
• treatment
• prognosis