Extraction of essential oil from Citrus reticulate Blanco peel and its antibacterial activity against Cutibacterium acnes (formerly Propionibacterium acnes)
He-Shuai Hou,
Emmanuel Mintah Bonku,
Rong Zhai,
Rong Zeng,
Ya-Li Hou,
Zhong-Hua Yang,
Can Quan
Affiliations
He-Shuai Hou
School of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan, 430081, China
Emmanuel Mintah Bonku
School of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan, 430081, China
Rong Zhai
School of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan, 430081, China
Rong Zeng
College of Chemistry and Chemical Engineering, Hubei University, Wuhan, 430062, China
Ya-Li Hou
School of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan, 430081, China
Zhong-Hua Yang
School of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan, 430081, China; Key Laboratory of Hubei Province for Coal Conversion and New Carbon Materials, Wuhan University of Science and Technology, Wuhan, 430081, China; Corresponding author.
Can Quan
Division of Chemical Metrology and Analytical Science, National Institute of Metrology, Beijing, 100029, China; Corresponding author.
Citrus is one of the largest output fruits in the word. In China, the major orange variety is the Citrus reticulate Blanco (Ponkan). The peels are discarded as waste material, its comprehensive utilization is urgently needed. In this work, hydrodistillation method was developed to extract citrus essential oil (EO) from Blanco peel. With the optimal extraction conditions, the EO yield was more than 3%. By GC-MS analysis, 53 compounds were identified from the citrus EO. Terpenes compounds accounted for 71.2%, especially d-limonene (major composition) accounted for 58.9%. The obtained citrus EO showed remarkable antibacterial activity against Cutibacterium acnes (C. acnes, Formerly P. acnes) and common microorganisms such as S. aureus, B. subtilis, and E. coli. Even compared with the common antibiotics (such as erythromycin, clindamycin, and tetracycline) for acne therapy, its antibacterial activity against C. acnes is more excellent. This work provides a potential therapy material for the treatment of acne.
