Ethyl 3-(4-fluorophenyl)-6-methyl-4-oxo-2-(1-cyclohexylamino)-3,4-dihydrofuro[2,3-d]pyrimidine-5-carboxylate

Abstract

In the crystal structure of the title compound, C22H24FN3O4, the two fused rings of furo[2,3-d]pyrimidine form a dihedral angle of 0.88 (13)°. The attached benzene ring is twisted with respect to the heterocyclic pyrimidinone ring, making a dihedral angle of 75.07 (12)°. The cyclohexyl ring shows a distorted chair conformation. The molecular structure is stabilized by intramolecular C—H...O and C—H...N hydrogen-bonding interactions. The crystal packing is mainly stabilized by C—H...π hydrogen-bond interactions. Further stability is provided by C—F...π and C—O...π stacking interactions.