P-71 EVALUATION OF ANXIETY AND DEPRESSION IN PATIENTS WITH CIRRHOSIS AND THE IMPACT ON THE QUALITY OF LIFE

Abstract

Introduction: Patients with cirrhosis develop multiple complications (ascites, hepatic encephalopathy, hemorrhage, etc.), which contribute to the deterioration of the quality of life, these patients can also present anxiety and/or depression, but few studies show the prevalence of these in these patients, as well as its impact on the quality of life. Objective: To determine the prevalence of anxiety and depression in patients diagnosed with liver cirrhosis and its impact on life quality. Methods: Observational, prospective, cross-sectional, and analytical study. Patients with a diagnosis of liver cirrhosis of any etiology and any stage, evaluated in consultation and hospitalization in the gastroenterology service, were included. The SF-36 questionnaire was applied for quality of life and the Hospital Anxiety and Depression Scale (HADS) screening anxiety and depression. Results: 108 patients were included, 55 (50.9%) men, and 53 (49.1%) women, aged 54.14 ± 11.29 years. The etiology: Due to alcohol 51 patients (47.2%), In patients with fatty liver associated with metabolic dysfunction (MAFLD) 24 patients (22.2%), autoimmune liver disease 16 patients (14.8%), chronic hepatitis C virus 10 patients (9.3 %), cryptogenic cirrhosis 7 patients (6.5%). The Child-Pugh stage: 48 patients (44.4%) A, 38 patients B (35.2%), and 22 patients C (20.4%). 84.3% of the patients had a primary caregiver. 26 patients (24.1%) were diagnosed with depression and 32 patients (29.6%) with anxiety. When evaluating SF36 of these patients, it was found that the 8 domains have deficient scores for emotional role and health. Conclusions: Patients with liver cirrhosis develop anxiety and depression, which are frequently not diagnosed or treated; In the group that we studied, the prevalence of anxiety and depression is much more frequent than that documented in the literature, as well as a deterioration in the quality of life-related to stress, depression, and progression of cirrhosis.