Scientific Data (Nov 2022)
MaHPIC malaria systems biology data from Plasmodium cynomolgi sporozoite longitudinal infections in macaques
- Jeremy D. DeBarry,
- Mustafa V. Nural,
- Suman B. Pakala,
- Vishal Nayak,
- Susanne Warrenfeltz,
- Jay Humphrey,
- Stacey A. Lapp,
- Monica Cabrera-Mora,
- Cristiana F. A. Brito,
- Jianlin Jiang,
- Celia L. Saney,
- Allison Hankus,
- Hannah M. Stealey,
- Megan B. DeBarry,
- Nicolas Lackman,
- Noah Legall,
- Kevin Lee,
- Yan Tang,
- Anuj Gupta,
- Elizabeth D. Trippe,
- Robert R. Bridger,
- Daniel Brent Weatherly,
- Mariko S. Peterson,
- Xuntian Jiang,
- ViLinh Tran,
- Karan Uppal,
- Luis L. Fonseca,
- Chester J. Joyner,
- Ebru Karpuzoglu,
- Regina J. Cordy,
- Esmeralda V. S. Meyer,
- Lance L. Wells,
- Daniel S. Ory,
- F. Eun-Hyung Lee,
- Rabindra Tirouvanziam,
- Juan B. Gutiérrez,
- Chris Ibegbu,
- Tracey J. Lamb,
- Jan Pohl,
- Sarah T. Pruett,
- Dean P. Jones,
- Mark P. Styczynski,
- Eberhard O. Voit,
- Alberto Moreno,
- Mary R. Galinski,
- Jessica C. Kissinger
Affiliations
- Jeremy D. DeBarry
- Institute of Bioinformatics, University of Georgia
- Mustafa V. Nural
- Institute of Bioinformatics, University of Georgia
- Suman B. Pakala
- Institute of Bioinformatics, University of Georgia
- Vishal Nayak
- Institute of Bioinformatics, University of Georgia
- Susanne Warrenfeltz
- Center for Tropical and Emerging Global Diseases, University of Georgia
- Jay Humphrey
- Institute of Bioinformatics, University of Georgia
- Stacey A. Lapp
- Emory Vaccine Center, Yerkes/Emory National Primate Research Center, Emory University
- Monica Cabrera-Mora
- Emory Vaccine Center, Yerkes/Emory National Primate Research Center, Emory University
- Cristiana F. A. Brito
- Emory Vaccine Center, Yerkes/Emory National Primate Research Center, Emory University
- Jianlin Jiang
- Emory Vaccine Center, Yerkes/Emory National Primate Research Center, Emory University
- Celia L. Saney
- Emory Vaccine Center, Yerkes/Emory National Primate Research Center, Emory University
- Allison Hankus
- Emory Vaccine Center, Yerkes/Emory National Primate Research Center, Emory University
- Hannah M. Stealey
- Institute of Bioinformatics, University of Georgia
- Megan B. DeBarry
- Institute of Bioinformatics, University of Georgia
- Nicolas Lackman
- Institute of Bioinformatics, University of Georgia
- Noah Legall
- Institute of Bioinformatics, University of Georgia
- Kevin Lee
- Center for Integrative Genomics, School of Biology, Georgia Institute of Technology
- Yan Tang
- School of Chemical & Biomolecular Engineering, Georgia Institute of Technology
- Anuj Gupta
- The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University
- Elizabeth D. Trippe
- Institute of Bioinformatics, University of Georgia
- Robert R. Bridger
- Complex Carbohydrate Research Center, Department of Biochemistry, University of Georgia
- Daniel Brent Weatherly
- Complex Carbohydrate Research Center, Department of Biochemistry, University of Georgia
- Mariko S. Peterson
- Emory Vaccine Center, Yerkes/Emory National Primate Research Center, Emory University
- Xuntian Jiang
- Division of Endocrinology, Metabolism & Lipid Research, Washington University School of Medicine
- ViLinh Tran
- Division of Pulmonary, Allergy, Critical Care, & Sleep Medicine, Department of Medicine, Emory University School of Medicine
- Karan Uppal
- Division of Pulmonary, Allergy, Critical Care, & Sleep Medicine, Department of Medicine, Emory University School of Medicine
- Luis L. Fonseca
- The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University
- Chester J. Joyner
- Emory Vaccine Center, Yerkes/Emory National Primate Research Center, Emory University
- Ebru Karpuzoglu
- Emory Vaccine Center, Yerkes/Emory National Primate Research Center, Emory University
- Regina J. Cordy
- Emory Vaccine Center, Yerkes/Emory National Primate Research Center, Emory University
- Esmeralda V. S. Meyer
- Emory Vaccine Center, Yerkes/Emory National Primate Research Center, Emory University
- Lance L. Wells
- Complex Carbohydrate Research Center, Department of Biochemistry, University of Georgia
- Daniel S. Ory
- Division of Endocrinology, Metabolism & Lipid Research, Washington University School of Medicine
- F. Eun-Hyung Lee
- Division of Pulmonary, Allergy, Critical Care, & Sleep Medicine, Department of Medicine, Emory University School of Medicine
- Rabindra Tirouvanziam
- Department of Pediatrics, Emory University School of Medicine
- Juan B. Gutiérrez
- Institute of Bioinformatics, University of Georgia
- Chris Ibegbu
- Emory Vaccine Center, Yerkes/Emory National Primate Research Center, Emory University
- Tracey J. Lamb
- Department of Pediatrics, Emory University School of Medicine
- Jan Pohl
- Biotechnology Core Facility Branch, Centers for Disease Control and Prevention
- Sarah T. Pruett
- Yerkes/Emory National Primate Research Center, Emory University
- Dean P. Jones
- Division of Pulmonary, Allergy, Critical Care, & Sleep Medicine, Department of Medicine, Emory University School of Medicine
- Mark P. Styczynski
- School of Chemical & Biomolecular Engineering, Georgia Institute of Technology
- Eberhard O. Voit
- The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University
- Alberto Moreno
- Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine
- Mary R. Galinski
- Emory Vaccine Center, Yerkes/Emory National Primate Research Center, Emory University
- Jessica C. Kissinger
- Institute of Bioinformatics, University of Georgia
- DOI
- https://doi.org/10.1038/s41597-022-01755-y
- Journal volume & issue
-
Vol. 9,
no. 1
pp. 1 – 43
Abstract
Measurement(s) parasitemia • blood Chemistry • reticulocyte count • platelet activation status • neutrophil and monocyte activation after stimulation • T-cell phenotyping • B-cell phenotyping • monocyte phenotyping • dendritic cell phenotyping • lymphocyte phenotyping • multiplexed cytokine assay • erythropoietin measurement • total IgG concentration • transcriptome • metabolomics • lipidomics • proteomics Technology Type(s) brightfield microscopy • iSTAT machine • immunological flow cytometry • chemokine receptor markers • intracellular staining • ELISA • LC/MS Factor Type(s) Parasitemia Sample Characteristic - Organism Macaca mulatta • Plasmodium cynomolgi B/M strain • Plasmodium cynomolgi Ceylon Sample Characteristic - Environment venous blood • capillary blood
