A tetracycline-dependent ribozyme switch allows conditional induction of gene expression in Caenorhabditis elegans

Lena A. Wurmthaler; Monika Sack; Karina Gense; Jörg S. Hartig; Martin Gamerdinger

doi:10.1038/s41467-019-08412-w

Nature Communications (Jan 2019)

A tetracycline-dependent ribozyme switch allows conditional induction of gene expression in Caenorhabditis elegans

Lena A. Wurmthaler,
Monika Sack,
Karina Gense,
Jörg S. Hartig,
Martin Gamerdinger

Affiliations

Lena A. Wurmthaler: Department of Chemistry, University of Konstanz
Monika Sack: Department of Chemistry, University of Konstanz
Karina Gense: Konstanz Research School Chemical Biology (KoRS-CB), University of Konstanz
Jörg S. Hartig: Department of Chemistry, University of Konstanz
Martin Gamerdinger: Konstanz Research School Chemical Biology (KoRS-CB), University of Konstanz

DOI: https://doi.org/10.1038/s41467-019-08412-w
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 8

Abstract

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Tools for conditional induction of gene expression in C. elegans are limited compared to other organisms. Here the authors present a tetracycline-dependent ribozyme that allows conditional control of a gene of interest.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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