Haematologica (Aug 2007)
Unrelated cord blood transplant in children with high-risk acute lymphoblastic leukemia: a long-term follow-up
Abstract
Background and Objectives The aim of this single center study was to assess the impact of pre-transplant factors on long-term follow-up in young patients affected by high-risk acute lymphoblastic leukemia (ALL) who underwent an unrelated cord blood transplant (CBT). The conditioning regimens, graft-versus-host disease (GVHD) prophylaxis and supportive policies were uniform for all patients.Design and Methods We analyzed the results of CBT performed in 30 patients, aged