A Mendelian randomization study of the effects of blood lipids on breast cancer risk

Christoph Nowak; Johan Ärnlöv

doi:10.1038/s41467-018-06467-9

Nature Communications (Sep 2018)

A Mendelian randomization study of the effects of blood lipids on breast cancer risk

Christoph Nowak,
Johan Ärnlöv

Affiliations

Christoph Nowak: Division of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet
Johan Ärnlöv: Division of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet

DOI: https://doi.org/10.1038/s41467-018-06467-9
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 7

Abstract

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The link between circulating lipids and breast cancer risk is complex. Here, the authors utilise data from more than 400,000 participants in two-sample Mendelian randomization to assess the link between blood lipids and breast cancer risk, and they find risk-promoting effects of raised LDL-cholesterol and CETP-mediated raised HDL-cholesterol.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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