TERATOGENIC PROPERTIES OF DRUGS. BACKGROUND INFORMATION

Abstract

The article presents the most significant steps in the development of ideas about drugs’ effects on fetus. It features the thalidomide tragedy and features of thalidomide teratogenic properties, as well as data on thalidomide syndrome prevention relevance in the 21st century. The article covers teratogenesis principles and gives information about the discovery of teratogenic properties and their manifestation in several other major teratogens: retinoids, carbamazepine, valproic acid, diethylstilbestrol.

Keywords

• pregnant women
• teratogenic properties
• drugs
• teratogenesis principles
• thalidomide
• retinoids
• carbamazepine
• valproic acid
• diethylstilbestrol