Research Progress of Androgen/Androgen Receptor Signaling Pathway in Hepatocellular Carcinoma

WANG Ruihua; CAI Shiliang; LIU Donghong; CHEN Hongsen; CAO Guangwen

doi:10.3971/j.issn.1000-8578.2023.22.0714

Zhongliu Fangzhi Yanjiu (Feb 2023)

Research Progress of Androgen/Androgen Receptor Signaling Pathway in Hepatocellular Carcinoma

WANG Ruihua,
CAI Shiliang,
LIU Donghong,
CHEN Hongsen,
CAO Guangwen

Affiliations

WANG Ruihua: Department of Epidemiology, Jinan University, Guangzhou 510632, China
CAI Shiliang: Department of Epidemiology, Naval Medical University, Shanghai 200433, China
LIU Donghong: Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai 200438, China
CHEN Hongsen: Department of Epidemiology, Naval Medical University, Shanghai 200433, China
CAO Guangwen: Department of Epidemiology, Naval Medical University, Shanghai 200433, China

DOI: https://doi.org/10.3971/j.issn.1000-8578.2023.22.0714
Journal volume & issue: Vol. 50, no. 2
pp. 180 – 185

Abstract

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Hepatocellular carcinoma (HCC) is a kind of primary liver cancer with a high mortality rate. In China, the incidence ratio in males to females with HCC is 2:1–5:1. The difference in sex hormone pathways between males and females and the interaction between androgen/androgen receptors and HBV can lead to an incidence difference between males and females with HCC. Hence, the androgen/androgen receptor oncogenic pathway in hepatocellular carcinoma has received considerable attention. This review mainly summarizes the recent research progress on the androgen/androgen receptor oncogenic pathway in hepatocellular carcinoma.

Published in Zhongliu Fangzhi Yanjiu

ISSN: 1000-8578 (Print)
Publisher: Magazine House of Cancer Research on Prevention and Treatment
Country of publisher: China
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: http://www.zlfzyj.com

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