Question about the Clinical Characteristics of Crimean Hemorrhagic Fever

Abstract

Background. The research was organized in order to analyze features of the main clinical symptoms in patients with Crimean hemorrhagic fever (CHF). Materials and methods. In furtherance of this goal 37 patients with the diagnosis of moderate CHF were exa­mined; they were treated at BPHF Nichoga Regional Clinical Hospital of Infectious Diseases during 2005–2016. Results. The main complaints were general weakness (100 %), diffuse headache (91 %), loss of appetite (76 %), arthralgias (80 %), giddiness (32 %), nausea (52 %), vomiting (46 %), myalgia (65 %) and arthralgia (78 %). Hemorrhagic syndrome manifested with petechial rash (79 %), post-injection (32.2 %) and traumatic (7.5 %) hematomas, blee­ding gums (52.3 %). Among cavity bleedings the examined patients had nasal (14.3 %), gastrointestinal (15.7 %), and microhematuria (18.3 %). There was no impairment of respiratory and cardiovascular systems. In 78 % of cases the symptoms of CNS dysfunction like retardation, bradyphrasia, rapid debilitating symptom and in several cases (8.1 %) a sleep disorder were noted. Conclusions. Thus, the clinical picture of the main symptoms of CHF testifies the existence of HS as a main pathogenetic factor of illness which influences the disease course and finally defines the forecast of the disease.