BRIEF COMMUNICATION: “Never say never” to transplant in aplastic anemia! A case study

Abstract

Severe aplastic anemia (SAA) is a rare bone marrow failure syndrome that results in a high risk of bleeding, infections, and impaired tissue repair. Allogeneic Hematopoietic Stem Cell Transplantation (Allo-HSCT) is a curative treatment option for eligible transplant patients and may be the only life-saving treatment option in patients with SAA with concurrent treatment-resistant infections (Bacigalupo, 2017). The following case study highlights a successful Allo-HSCT in a patient with SAA with multiple treatment-resistant infections secondary to a large non-healing perianal wound. The discussion focuses on the creative approach that was guided by specialized point-of-care oncology nurses, a specialized oncology wound care nurse, and oncology nurse practitioners in collaboration with the multidisciplinary team.